Nutrigenomics and Epigenetics – The Future of Personalised Health in Australia

Nutrigenomics and Epigenetics

The Shift Toward Personalised Healthcare

In recent years, Australia has seen a steady rise in demand for personalised and preventative approaches to health. At the forefront of this movement are two powerful scientific fields: nutrigenomics and epigenetics. These disciplines are transforming how we understand the impact of food, lifestyle, and environment on our genes, and ultimately, our wellbeing.

For Australians navigating chronic illness, unexplained symptoms, or simply seeking better vitality, these fields offer a more targeted and proactive path to health.

What is Nutrigenomics?

Nutrigenomics is the study of how your genes interact with nutrients in your diet. It helps determine how different people metabolise foods, absorb nutrients, or respond to specific dietary patterns.

For example:

  • One person may thrive on a high-fat diet, while another may experience inflammation or weight gain.
  • Some may need more B vitamins due to variations in their MTHFR gene.

Others may be at higher risk for insulin resistance or cardiovascular issues depending on their genetic profile.

Nutrigenomics and Epigenetics

What is Epigenetics?

Epigenetics refers to how lifestyle and environment can influence gene expression—turning genes on or off without changing your DNA itself.

It’s a key concept in understanding why:

  1. Two people with the same genetic variant might have very different health outcomes
  2. Chronic stress, poor diet, toxins, and inactivity can trigger or suppress disease processes

Most importantly: epigenetic changes are reversible, giving us hope for interventions that improve long-term health.

Nutrigenomics & Epigenetic Testing in Australia

More Australians are now accessing DNA-based health reports through practitioners or online platforms. In my testing and analysis, I provide information on:

  • Nutrient requirements (e.g. omega-3s, B vitamins, fats, carobydrates etc )
  • Food sensitivities an (eg gluten, dairy)
  • Detoxification pathways
  • Inflammatory markers
  • Methylation capacity
  • Exercise recovery
  • Hormone metabolism
  • Biological processes associated with maternal and baby health throughout pregnancy
  • Risk for certain autoimmune conditions & more.  

This helps me to then design precision diet, lifestyle and supplemental therapeutic strategies based on an individuals particular genetic blueprint.

Nutrigenomics: The Australian Market Snapshot

  • Over 30% of Australians are interested in personalised nutrition, especially for weight loss, chronic fatigue, hormonal conditions, inflammatory conditions,  mood disorders or optimising fertility.
  • According to the Australian Institute of Health and Welfare, 50% of adults live with a chronic disease—many of which are preventable or modifiable through personalised intervention.

Epigenetic therapy is also being explored in Australian research for cancer and autoimmune conditions.

Who Benefits from Nutrigenomic Testing?

This testing is valuable for individuals experiencing:

MTHFR, COMT, APOE and Other Genes to Know

Some common genes that influence health outcomes include:

  • MTHFR – B-vitamin metabolism, methylation, cardiovascular health
  • COMT – Mood, dopamine regulation, stress response
  • APOE – Cardiovascular and brain health
  • FTO – Obesity and metabolism
  • GST/GPX – Detox and oxidative stress

Knowing your gene variations allows for tailored supplementation, dietary changes, and lifestyle hacks.

Ethical & Privacy Considerations

As with any form of genetic testing, it’s crucial to choose to work with trained practitioners to avoid misinterpretation.

Nutrigenomics in Functional and Preventative Medicine

Practitioners like myself trained in functional medicine and naturopathy, use nutrigenomics as part of a root-cause approach. Instead of treating symptoms, we optimise underlying systems using a blend of:

  • Functional DNA testing  
  • Methylation assessesmts
  • Functional pathology analysis of 30-90 key biomarkers
  • Epigenetic assessments
  • Functional tests (e.g. gut microbiome testing, DUTCH hormone testing, organic acid testing, TruAge epigenetic testing etc.)
  • Naturopathic interventions (eg diet modifications, lifestyle coaching, herbal and nutraceutical supplementation)

It’s not about diagnosing genetic disease—it’s about using genetics to prevent disease and optimise health.

References & Resources

  • Australian Institute of Health and Welfare – Chronic Disease
  • De Caterina, R., Martinez, J. A., & Kohlmeier, M. (2020). Principles of nutrigenetics and nutrigenomics: Fundamentals of individualised nutrition. Elsevier.
  • DNA Life
  • Fitgenes
  • myDNA Australia
  • NHMRC Epigenetics Research
  • OAIC – Privacy and Genetic Data

Disclaimer: The information provided in this blog article is for educational and informational purposes only and does not constitute medical advice and reliance on this information is at your own risk. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always consult personally with a qualified healthcare professional for any health concerns or before making any medical decisions. The author of this article is not liable for any decisions or actions taken based on the information provided and is not liable for any damages, injuries, or losses that may result from relying on the information provided on this blog. By using this blog, you agree to release the author from any and all claims, demands, and actions arising from your use of the information provided

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